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Ursolic acid

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[Product name]: Ursolic acid

[Outside View]: White Powder

[active ingredient]: ursolic acid

[Package]: 25KG / bucket

[English name] Uosonic Aid

[Other Name] Ursoic acid, Ursoic acid

[Extract source] Eriotorya japonica(Thunb. ) Lindl leaves.

[Molecular formula] C30H48O3

[Molecular weight] 456.68

CAS No. 77-52-1

[Regulation] 80 % 90 % 95 % 98 %

MP 240-245 °C

[purity] 98 %

[Chemical name] 3-Hydroxy-12-ursen-28-oic aid

[Chemical structure formula]

[Plant Introduction]

<unk> <unk>, alias: Lu Orange, Jin Wan, Lu Zhi, Latin name: Eriotorya japonica(Thunb. ) Lindl. Rosaceae, a genus of plants, is native to southeastern China. It is named after the shape of the leaves like a musical instrument. Its flowers can be used as medicine. The height of the tree is 3 to 5 meters. The leaves are large and long, thick and hairy, with a long oval shape and shape. Alias are also called Lu

Orange, Luzhi, Jinwan, Yanguo, Jiaozi.

Distribution Range

Production Gansu, Shaanxi, Henan, Jiangsu, Anhui, Zhejiang, Jiangxi, Hubei, Hunan, Sichuan, Yunnan, Guizhou, Guangxi, Guangdong, Fujian, Taiwan. Widely cultivated everywhere, there are wild people in Sichuan and Hubei. Japan, India, Vietnam, Myanmar, Thailand, and Indonesia also have cultivation.

Tangqi soft strips Baisha in Yuhang District, Hangzhou City, Zhejiang Province, Dongshan, Suzhou(according to the species of Baisha <unk> <unk>) and Baokeng Liberation Bell in Putian, Fujian Province, are the three major producing areas in China.

[Physical properties]

The high content of ursolic acid is shiny Prismatic(anhydrous ethanol) or fine hair-like needle-like crystal(dilute ethanol), and the low content is brownish-yellow or yellow-green powder, with a special odor, which is present in natural plants. A pentacyclic triterpenoids compound. Melting point 283 ~ 288 °C. Specific rotation[ Α] D25 +67.5 °(C = 1, 1 mol/L potassium hydroxide solution). in

At 15 °C, ethanol(99 %) 1 ml can dissolve 10 mg and boiling 1 ml can dissolve 45 mg. It is still soluble in methanol, acetone, pyridine, insoluble in water and petroleum ether.

[Test conditions]

In order to better separate ursolic acid from oleanolic acid, a famous foreign company's chromatographic column is used. The reason is that the company summarized the results during the production process. Adopt Anjilon C18 column, to B

Nitrile: Water(volume to volume ratio 93:7) solution is a mobile phase, detected by ultraviolet detector at 210 nm. Ethanol dissolution, contrast solution 8-12 mg / 25M.

[Production process]

The crushed loquat leaves or privet leaves are extracted with ethanol reflux to obtain an extract of liquid extract and recovered ethanol. The above extracts are fully washed with water and dried to obtain a dry extract. The dry extract is dissolved with ethanol and decolorized. After recovering ethanol, the decolorized liquid is added with water to precipitate a large amount of precipitation. Adjust pH to 2-2 .5, separate, collect sediment, and wash with water to neutral, true

Empty and dry to obtain a coarse extract consisting mainly of ursolic acid.


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